发明名称 Process for preparation of diphosphine compounds and intermediates for the process
摘要 A production method of a compound represented by the formula wherein R1a, R1b, R1c, R1d, R1e, R1f, R2a, R2b, R2c, R2d, R2e and R2f are the same or different and each is a hydrogen atom and the like, and R3, R4, R5, R6, R7, R8, R9 and R10 are the same or different and each is a hydrogen atom and the like, or a salt thereof, which comprises reacting a compound represented by the formula wherein X is a leaving group and other symbols are as defined above, or a salt thereof, with a phosphine-borane complex represented by the formula wherein the symbols are as defined above, or a salt thereof, in a solvent in the presence of an amine and a nickel catalyst, is provided.
申请公布号 US8053604(B2) 申请公布日期 2011.11.08
申请号 US20100694658 申请日期 2010.01.27
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 GOTO MITSUTAKA;YAMANO MITSUHISA
分类号 C07F5/02;C07F9/46;C07F9/50;C07F9/655 主分类号 C07F5/02
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