INJECTABLE CROSS-LINKED POLYMERIC PREPARATIONS AND USES THEREOF

摘要

PROBLEM TO BE SOLVED: To provide a composition for promoting repair of damaged tissue of cardiac tissue post-myocardial infarct.

SOLUTION: A therapeutic composition, containing an aqueous solution of an alginate cross-linked by calcium cations, wherein the alginate has a molecular weight ranging from 25 to 250 kDa and a concentration of 1% (w/v). The calcium cation is a therapeutic composition featured by being given by calcium gluconate in a concentration of about 0.3% (w/v). The composition can be maintained in liquid form indefinitely (under constant conditions) and gels only in vivo. A kit for tissue repair is also provided.

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