| 摘要 |
<p>Provided is a skin irritation suppressant for transdermal preparations, said skin irritation suppressant having an acknowledged effect of adequately reducing skin irritation caused by drugs. Also provided is a transdermal preparation containing said skin irritation suppressant. One embodiment of the invention is a skin irritation suppressant for reducing skin irritation caused by pharmaceutical adjuvants used in drugs and transdermal preparations other than drugs, said skin irritation suppressant comprising sterol compounds selected from a group comprising cholesterol, cholesterol derivatives and cholesterol analogs. Said drug is one or more basic drugs selected from a group comprising tolterodine, asenapine, bisoprolol, risperidone, nicotine, and mitalopram, and pharmacologically acceptable salts thereof.</p> |
