发明名称 |
Orally disintegrating tablets and methods of manufacture |
摘要 |
<p>A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drug, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.</p> |
申请公布号 |
AU2005237411(C1) |
申请公布日期 |
2011.11.03 |
申请号 |
AU20050237411 |
申请日期 |
2005.03.31 |
申请人 |
EURAND PHARMACEUTICALS LIMITED |
发明人 |
VANGALA, SHYAM;CLEVENGER, JAMES M.;GUENTHER, DONALD;VENKATESH, GOPI M.;QIAN, KEN KANGYI |
分类号 |
A61K9/00;A61K9/16;A61K9/20;A61K9/46;A61K9/50;A61K31/34 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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