发明名称 |
Ex-vivo treatment of peripheral blood leukocytes with IFN-lambda |
摘要 |
The present invention provides an ex vivo method of treating plasmacytoid dendritic cells (pDC) in Th2- or Th17-associated diseases by modulating the cytokine expression or secretion using interferon lambda (IFN-λ). For the Th-2 or Th17-associated diseases, pDC cells from a patient having the disease are exposed ex vivo with IFN-λ in an effective amount to inhibit cytokine releases. The IFN-λ exposed pDC are administered back into the patient. The present invention also provides a method of ex vivo IFN-λ treatment of pDC, in conjunction with co-administration of a composition comprising IFN-λ.
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申请公布号 |
US2011268707(A1) |
申请公布日期 |
2011.11.03 |
申请号 |
US20090592635 |
申请日期 |
2009.11.30 |
申请人 |
MEDICAL DIAGNOSTIC LABORATORIES, LLC |
发明人 |
GALLAGHER GRANT;MEGJUGORAC NICHOLAS;GALLAGHER GRANT E. |
分类号 |
A61K35/12;A61P1/00 |
主分类号 |
A61K35/12 |
代理机构 |
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