NOVEL TABLET COMPOSITION OF POLYALLYLAMINE POLYMERS

摘要

The present invention relates to pharmaceutical compositions comprising polyallylamine polymer, binder, disintegrant, diluents and pharmaceutically acceptable inert excipients, substantially free of cellulose or cellulose derivatives and stearic acid. The polyallylamine polymer includes such as sevelamer hydrochloride, sevelamer carbonate and colesevelam hydrochloride. Particularly, the present invention provides pharmaceutical composition comprising a tablet core substantially free of cellulose. Moreover, the present invention relates to a process of preparing the pharmaceutical composition in tablet form by direct compression method.