发明名称 |
MICROCRYSTALLINE CELLULOSE AND CALCIUM PHOSPHATE COMPOSITIONS USEFUL AS PHARMACEUTICAL EXCIPIENTS |
摘要 |
Coprocessed compositions containing calcium phosphate and microcrystalline cellulose are useful as excipients in the preparation of solid dosage forms containing active pharmaceutical ingredients, particularly those prepared by processes involving multiple compaction steps. Such compositions may be obtained by preparing aqueous slurries of microcrystalline cellulose and calcium phosphate and drying such slurries to produce particulate products. The coprocessed products exhibit improved compactibility, as compared to dry physical blends of the same components. |
申请公布号 |
WO2011056775(A3) |
申请公布日期 |
2011.11.03 |
申请号 |
WO2010US55068 |
申请日期 |
2010.11.02 |
申请人 |
FMC CORPORATION;THOORENS, GREGORY;LECLERCQ, BRUNO;RUSZKAY, THOMAS |
发明人 |
THOORENS, GREGORY;LECLERCQ, BRUNO;RUSZKAY, THOMAS |
分类号 |
A61K47/04;A61K9/16;A61K9/20;A61K47/02;A61K47/30;A61K47/38 |
主分类号 |
A61K47/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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