| 摘要 |
A cell collecting device (10, 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140, 170) having a housing (12) with an inlet (16, 56, 66, 76, 86, 96, 106, 116, 126, 136, 146, 176) for receiving cells, a cell attractant cavity (14, 54, 64, 74, 84, 94, 104, 114, 124, 134, 144, 174) have a cell attractant, a cell collection channel (18, 58, 68, 78, 88, 98, 108, 118, 128, 138, 148, 178) running from the inlet to the cell attractant cavity, and a plurality of electrodes (20) positioned to detect the presence of cells is disclosed. The cell attractant cavity may include a porous medium (29, 59, 69, 79, 89, 99, 119, 129, 139, 149, 179A, 179B), such as, a hydrogel, containing the cell attractant, such as, epidermal growth factor. The channel may include a plurality of restrictions (93, 113, 123, 143, 173) and expansions or chambers (115, 125, 135, 145, 175) to assist in maintaining the porous medium while permitting the passage of attractant and cells. The device may be implanted into a patient for an extended period of time, and then removed and examined. A method for collecting cells, an implantable attractant dispersing device, and a porous medium for controlled releasing of a compound are also disclosed. |
