发明名称 CATIONIC LIPID
摘要 Disclosed is a cationic lipid which is represented by formula (I) and makes it easier to introduce a nucleic acid into a cell. (In formula (I), R1 and R2 may be the same or different and each represents an alkenyl group or the like; X1 and X2 each represents a hydrogen atom, or alternatively X1 and X2 combine together to form a single bond or an alkylene group; X3 is absent or represents an alkyl group or the like; Y is absent or represents an anion; a and b may be the same or different and each represents a number of 0-3; L3 represents a single bond or the like; R3 represents an alkyl group or the like; and L1 and L2 each represents -O-, -CO-O- or -O-CO-.) Also disclosed are: a composition that contains the cationic lipid and a nucleic acid; and a method for introducing a nucleic acid into a cell, using the composition that contains the cationic lipid and a nucleic acid.
申请公布号 WO2011136368(A1) 申请公布日期 2011.11.03
申请号 WO2011JP60458 申请日期 2011.04.28
申请人 KYOWA HAKKO KIRIN CO., LTD.;KUBOYAMA, TAKESHI;ERA, TOMOHIRO;NAOI, TOMOYUKI 发明人 KUBOYAMA, TAKESHI;ERA, TOMOHIRO;NAOI, TOMOYUKI
分类号 C07C217/28;A61K47/16;A61K48/00;A61P29/00;A61P35/00;C07C219/20;C07C233/18;C07D207/08;C07D207/12;C12N15/00 主分类号 C07C217/28
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