Vaccines comprising attenuated mycoplasma bovis strains and method for the attenuation

摘要

The present invention relates to new attenuated mycroplasma bovis bacteria strains passaged at least 110 times. Moreover, the present invention also provides immunogenic compositions comprising live bacteria of any of those attenuated M. bovis bacteria strain, their manufacture and use for the treatment and prophylaxis of M. bovis infections and combinations with other veterinary vaccines or medicaments.