| 摘要 |
A method for inhibiting and/or reversing replicative senescence is provided comprising a step of administering a therapeutically effective amount of a compound which mediates allosteric modulation of beta 1 integrin to a subject in need thereof. Typically the allosteric modulation of beta 1 integrin results in beta 1 integrin assuming an intermediate affinity state conformation. The method of the present invention may be used in the treatment and/or prevention of ageing and ageing-related conditions.
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