Methods for detecting multiple targets in a biological sample are provided. The methods include (a) contacting the sample with a first probe; (b) physically binding the first probe to a first target; (c) detecting a first signal from the first probe; (d) applying a chemical agent to modify the first signal; (e) contacting the sample with a second probe; (f) physically binding the second probe to a second target; and (g) detecting a second signal from the second probe. An associated kit and device are also provided.
申请公布号
EP2383574(A2)
申请公布日期
2011.11.02
申请号
EP20110175305
申请日期
2007.11.15
申请人
GENERAL ELECTRIC COMPANY
发明人
FILKINS, ROBERT, JOHN;MONTALTO, MICHAEL, CHRISTOPHER;SOOD, ANUP;GERDES, MICHAEL, J;SEEL, MAXIMILIAN, LEWIS