发明名称 |
MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS |
摘要 |
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
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申请公布号 |
CA2653034(C) |
申请公布日期 |
2011.11.01 |
申请号 |
CA20072653034 |
申请日期 |
2007.06.06 |
申请人 |
ENANTA PHARMACEUTICALS, INC. |
发明人 |
SUN, YING;NIU, DEQIANG;XU, GUOYOU;OR, YAT SUN;WANG, ZHE |
分类号 |
C07D487/04;A61K31/395;A61K31/407;A61P31/14;C07D519/00 |
主分类号 |
C07D487/04 |
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地址 |
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