6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H BENZO [d] AZEPINES AS 5-HT2C RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS

摘要

The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT 2C receptor agonists for the treatment of 5-HT 2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety:
where:
R 6 is -S-L-R 15
and other substituents are as defined in the specification.