发明名称 |
TRIAZOLYL PHENYL BENZENESULFONAMIDES |
摘要 |
Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists. |
申请公布号 |
EA015710(B1) |
申请公布日期 |
2011.10.31 |
申请号 |
EA20090000168 |
申请日期 |
2007.07.10 |
申请人 |
CHEMOCENTRYX, INC. |
发明人 |
CHARVAT TREVOR, T.;HU CHENG;MELIKIAN ANITA;NOVACK AARON;PENNELL ANDREW, M.K.;SULLIWAN EDWARD, J.;TAN XUEFEI;THOMAS WILLIAM, D.;UNGASHE SOLOMON;ZENG YIBIN;PUNNA SREENIVAS |
分类号 |
C07D249/08;A61K31/41;A61P29/00;C07D401/04;C07D403/04;C07D405/04;C07D405/12;C07D413/04 |
主分类号 |
C07D249/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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