Disclosed is a cyclic peptide of formula (I) where SI is the divalent radical p-aminobenzyloxycarbonyl, CT represents a cytotoxic radical and the other variables are as disclosed in the description. Also disclosed is the use of a peptide of formula (I) in the manufacture of a medicament to treat cancer, the process for preparing a peptide of formula (I) and a pharmaceutical composition comprising a peptide of formula (I).
申请公布号
NZ588948(A)
申请公布日期
2011.10.28
申请号
NZ20090588948
申请日期
2009.05.11
申请人
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
发明人
DAL POZZO, ALMA;ESPOSITO, EMILIANO;NI, MINGHONG;PENCO, SERGIO;PISANO, CLAUDIO;CASTORINA, MASSIMO;VESCI, LOREDANA