2-[(2-SUBSTITUTED)-INDOLIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS
摘要
Disclosed is an indolizinyl compound of formula (I) where the substituents are as disclosed in the specification. Also disclosed is a pharmaceutical composition comprising a compound of formula (I), the use of a compound of formula (I) in the manufacture of a medicament to treat fungal disease especially an agricultural fungicide and a method of controlling a fungal disease in a plant using a compound of formula (I). Examples of compounds of formula (I) are N-[ 4-(2-Morpholin-4-yl-ethoxy)-phenyl]-2-oxo-2-(2-phenyl-indolizin-3-yl)-acetamide; 2-Hydroxy-4-[2-oxo-2-(2-phenyl-indolizin-3-yl)-acetylamino ]-benzoic acid tetrahydropyran-4-yl ester and 2-Isopropyl-4-[2-oxo-2-(2-phenyl-indolizin-3-yl )-acetylamino ]-benzoic acid 2-(2-isopropyl-imidazol-1-yl)-ethyl ester.