| 发明名称 |
METHOD TO IMPROVE THE IMMUNOGENICITY OF VACCINE ANTIGENS BY MODIFICATION OF CLEAVAGE SITES IN HIV-1 GP 120 |
| 摘要 |
Disclosed are novel methods for altering the immunogenicity of vaccine antigens by mutation of cleavage sites recognized by proteases involved in antigen presentation and processing. Also disclosed are therapeutic compositions, vaccines and methods for treating or preventing HIV and other viral diseases. |
| 申请公布号 |
WO2011057160(A3) |
申请公布日期 |
2011.10.27 |
| 申请号 |
WO2010US55747 |
申请日期 |
2010.11.05 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;BERMAN, PHILIP |
发明人 |
BERMAN, PHILIP |
| 分类号 |
A61K38/57;A61P31/18;C12N15/11;C12Q1/68 |
主分类号 |
A61K38/57 |
| 代理机构 |
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代理人 |
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