| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, and concerns mediated PHKi inhibition of RHO-kinase for treating ophthalmic disorders. The substance of the invention involves RNA-interference for mRNA Rho-kinase expression inhibition for treating patients with ophthalmic disorders, especially for treating intraocular pressure, eye hypertension and glaucoma The mRNA Rho-kinase targets include gene ROCK 1 mRNA. ^ EFFECT: creation of the agent exhibiting improved properties. ^ 56 cl, 2 ex, 4 dwg, 1 tbl |
