COMPOSITIONS COMPRISING TRYPSIN-CLEAVABLE AMPHETAMINE PRODRUGS AND INHIBITORS THEREOF
摘要
<p>Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise an amphetamine prodrug that provides enzymatically-controlled release of amphetamine or an amphetamine analog. The composition can further comprise an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of amphetamine or the amphetamine analog from the amphetamine prodrug so as to attenuate enzymatic cleavage of the amphetamine prodrug.</p>
申请公布号
WO2011133347(A1)
申请公布日期
2011.10.27
申请号
WO2011US31845
申请日期
2011.04.08
申请人
PHARMACOFORE, INC.;JENKINS, THOMAS E.;HUSFELD, CRAIG O.;SEROOGY, JULIE D.;WRAY, JONATHAN W.
发明人
JENKINS, THOMAS E.;HUSFELD, CRAIG O.;SEROOGY, JULIE D.;WRAY, JONATHAN W.