| 发明名称 |
MODULATION OF NK CELL ANTIGEN SPECIFIC EFFECTOR ACTIVITY BY MODULATION OF CXCR6 (CD186) |
| 摘要 |
The instant invention is based, at least in part, on the discovery that CXCR6 plays a critical role in antigen- specific effector function of NK cells. Accordingly, the invention provides, among other things, methods for modulation of antigen- specific NK cell effector function, methods for identifying modulators of antigen- specific NK cell effector function. |
| 申请公布号 |
WO2011068870(A3) |
申请公布日期 |
2011.10.27 |
| 申请号 |
WO2010US58561 |
申请日期 |
2010.12.01 |
| 申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;VON ANDRIAN, ULRICH;PAUST, SILKE |
发明人 |
VON ANDRIAN, ULRICH;PAUST, SILKE |
| 分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
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