发明名称 AAV-BASED TREATMENT OF CHOLESTEROL-RELATED DISORDERS
摘要 The invention in some aspects relates to methods and compositions for assessing the effectiveness of miRNA inhibitors. In other aspects of the invention, methods and compositions for treating cholesterol related disorders are provided. In one aspect of the invention, miRNA inhibitors against miR-122 and rAAV-based compositions comprising the same are provided.
申请公布号 CA2833912(A1) 申请公布日期 2011.10.27
申请号 CA20112833912 申请日期 2011.04.22
申请人 UNIVERSITY OF MASSACHUSETTS 发明人 GAO, GUANGPING;XIE, JUN;ZAMORE, PLILLIP D.
分类号 C12N15/113;A61K31/7088;A61P3/06;C07H21/00;C12N15/63;C12N15/864;C12Q1/68 主分类号 C12N15/113
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