发明名称 1-Phenylpyrrole Derivatives
摘要 The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1-C3 alkyl group; R2 represents a hydroxy-C1-C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1-C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like,—R5 represents a sulfamoyl group or a C1-C3 alkylsulfonyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.
申请公布号 US2011263544(A1) 申请公布日期 2011.10.27
申请号 US200913122239 申请日期 2009.10.07
申请人 DAIICHI SANKYO COMPANY, LIMITED;EXELIXIS, INC. 发明人 NUSS JOHN;WILLIAMS MATTHEW;MOHAN RAJU;MARTIN RICHARD;WANG TIE-LIN;TSURUOKA HIROYUKI;AOKI KAZUMASA;HONZUMI MASATOSHI;ASOH YUSUKE;SAITO KEIJI;HOMMA TSUYOSHI
分类号 A61K31/635;A61K31/402;A61P5/42;A61P7/10;A61P9/10;A61P9/12;A61P13/12;C07D207/34;C12N5/071 主分类号 A61K31/635
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