<p>The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.</p>
申请公布号
AU2007254942(B2)
申请公布日期
2011.10.27
申请号
AU20070254942
申请日期
2007.06.01
申请人
AVEO PHARMACEUTICALS, INC.;XOMA TECHNOLOGY LTD.
发明人
HAN, MAY;KNUEHL, CHRISTINE;HORWITZ, ARNOLD;BREAULT, LYNE;LIN, JIE;WINSTON, WILLIAM M.;GYURIS, JENO;ETEMAD-GILBERTSON, BIJAN;WRIGHT, S. KIRK