发明名称 2-OXO-3-BENZYLBENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMOURS
摘要 Described are compounds which inhibit, regulate and/or modulate kinase signal transduction, for example of Met kinase. The compounds are of the formulae A1 to A148 and B1 described herein, including 2-oxobenzoxazol-3-ylmethyl]phenyl}carbamate and 2-oxooxazolo[4,5-b]pyridin-3-ylmethyl)phenyl]carbamate compounds, and pharmaceutically usable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. Also described are compositions containing these compounds. Also described are methods for the treatment of diseases in which the inhibition, regulation and/or modulation of kinase signal transduction plays a role by administering these compounds.
申请公布号 US2011263596(A1) 申请公布日期 2011.10.27
申请号 US201113177261 申请日期 2011.07.06
申请人 SCHADT OLIVER;DORSCH DIETER;STIEBER FRANK;BLAUKAT ANDREE 发明人 SCHADT OLIVER;DORSCH DIETER;STIEBER FRANK;BLAUKAT ANDREE
分类号 A61K31/5377;A61K31/423;A61K31/4245;A61K31/437;A61K31/4439;A61K31/4545;A61K31/496;A61K31/501;A61K31/506;A61P35/00;A61P35/02 主分类号 A61K31/5377
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