| 摘要 |
PROBLEM TO BE SOLVED: To provide a simple synthetic path for selectively producing a 5, 6-substituted indanone.SOLUTION: The method for producing an indanone derivative represented by formula (1) includes reacting a compound represented by formula (2) with a compound represented by formula (3) in a compound represented by formula (4) in the presence of a Lewis acid catalyst (wherein the formula containing Q in the left end in the figure α is the central formula or the right formula; R-Rare each the same or different and alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, aryl, alkoxy, aralkyloxy, aryloxy, silyl, amino or heterocyclic compound residue; R-Rare each the same or different hydrogen atom, alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, aryl, alkoxy, aralkyloxy, aryloxy, silyl, amino or heterocyclic compound residue; Rand R, Rand R, Rand R, Rand R, Rand Rand Rand Reach may be bonded to form a ring; the ring may contain a substituent; X is a chlorine atom, bromine atom or iodine atom; Ris as shown above: Rs are each a halogen atom or alkyl; n is an integer of 1-6; when n is ≥2, Rs may be the same or different). |
