RECOMBINANT MUTANT MICROORGANISM WITH INCREASED ALCOHOL PRODUCTION ABILITY, AND PREPARATION METHOD OF ALCOHOL USING SAME

摘要

The present invention relates to a recombinant mutant microorganism with an increased alcohol production ability, and a preparation method of alcohol using the same, and more specifically, to a recombinant mutant microorganism which hardly produces acetone as a by-product and has an increased production ability of butanol, ethanol, isopropanol or an alcohol mixture capable of being used as fuel, and a preparation method of butanol, ethanol, isopropanol or an alcohol mixture using the same. The recombinant mutant microorganism with an increased production ability of butanol or an alcohol mixture and an acetone removing ability according to the present invention is characterized in that a gene encoding an enzyme involved in the production of butanol from butyryl-CoA or butylaldehyde and involved in the production of isopropanol from acetone is amplified or introduced into a host microorganism. Since the recombinant mutant microorganism according to the present invention hardly produces by-products such as acetone and the like by the manipulation of metabolic flow and can improve alcohol productivity, it is useful for the industrial production of butanol or an alcohol mixture comprising butanol and isopropanol.