Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases

摘要

The present application concerns multimers of MHC-peptide complexes, in particular, dextramers, wherein the peptide is a 9-mer derived from a Borrelia outer surface protein antigen. The application is also directed to compositions, kits and vaccines comprising said MHC multimers and uses thereof in immuno-monitoring, diagnosis, and therapy, especially to detect specific T cells.