发明名称 |
COMBINATION OF PHOTODYNAMIC THERAPY AND ANTI-VEGF AGENTS IN THE TREATMENT OF UNWANTED CHOROIDAL NEOVASCULATURE |
摘要 |
The use of a combination of photodynamic therapy and an anti-VEGF agent in the treatment of conditions characterized by unwanted choroidal neovasculature is described. These conditions include wet age-related macular degeneration Preferred anti-VEGF agents are antibodies such as bevacizumab or ranibizumab Photosensitizers may be selected from green porphyrins such as BPD-MA (verteporfin) and the photodynamic activation of the photo sensitizer may be accomplished using a reduced fluence rate. The use may further comprises an anti-inflammatory agent such as dexamethasone. |
申请公布号 |
EP2379109(A1) |
申请公布日期 |
2011.10.26 |
申请号 |
EP20090832787 |
申请日期 |
2009.12.16 |
申请人 |
QLT INC. |
发明人 |
STRONG, H. ANDREW;HAO, YONG |
分类号 |
A61K41/00;A61K31/409;A61K31/573;A61K39/395;A61P27/02;C07K16/22 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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