发明名称 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS AND USE THEREOF
摘要 Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases.
申请公布号 UA96284(C2) 申请公布日期 2011.10.25
申请号 UA20080009431 申请日期 2007.01.22
申请人 NOVARTIS AG 发明人 BURGER MATTHEW;NI ZHI-JIE;PECCHI SABINA;ATALLAH GORDANA;BARTULIS SARAH;FRAZIER KELLY;SMITH, AARON;VERHAGEN JOELLE;ZHANG YANCHEN;WAGMAN ALLAN;NG SIMON;PFISTER KEITH;POON DANIEL;LOUIE ALICIA;PICK TERESA E.;BARSANTI PAUL;IWANOWICZ EDWIN;FANTL WENDY;HENDRICKSON THOMAS;KNAPP MARK;MERITT HANNE;VOLIVA CHARLES;WIESMANN MARION;XIN XIAHUA
分类号 C07D401/04;A61K31/506;C07D401/14;C07D405/12;C07D405/14;C07D417/12 主分类号 C07D401/04
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