METHOD FOR ESTABLISHING AND PREDICTING RESISTANCE OR RESPONSIVENESS TO CHEMOTHERAPY USING PROTEIN PROFILE
摘要
<p>The present invention is directed to a method to predict responsiveness or resistance to chemotherapy in breast cancer comprising providing an optionally processed sample from a breast cancer patient as a test sample, wherein the sample comprise peptides proteins and/or genes; determining the amount of individual peptides, proteins and/or genes in the sample comparing the amount of an individual peptide and/or protein or the presence of a gene present in the test sample with the amount of a corresponding peptide or protein in a reference sample, wherein the individual peptide or protein in the test sample is selected from the group consisting SEQ ID 1-73 or proteins identified in table 3 and 4 or genes encoding for the peptides or proteins.</p>
申请公布号
WO2011129685(A1)
申请公布日期
2011.10.20
申请号
WO2010NL50199
申请日期
2010.04.15
申请人
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM;UMAR, ARZU;FOEKENS, JOHANNES ALBERT;LUIDER, THEO, MARTEN
发明人
UMAR, ARZU;FOEKENS, JOHANNES ALBERT;LUIDER, THEO, MARTEN