发明名称 |
METHODS FOR DETECTING TUMOR ORIGIN BASED ON MUC1, MUC2, AND CK-17 EXPRESSION LEVELS |
摘要 |
<p>Methods and compositions for detecting tumor origin are disclosed. In certain embodiments, the origin is determined by detecting expression levels of pan-epithelial membrane mucin (MUC1), intestinal-type secretory mucin (MUC2), cytokeratin 17 (CK17), or a combination thereof. Also disclosed are methods for aiding in the determination of an appropriate course of treatment for a subject with a tumor, or for predicting a therapeutic outcome of a subject, based on the expression levels of MUC1, MUC2, CK17, or a combination thereof. Kits for use in each of these methods are also provided.</p> |
申请公布号 |
WO2011130640(A1) |
申请公布日期 |
2011.10.20 |
申请号 |
WO2011US32702 |
申请日期 |
2011.04.15 |
申请人 |
ESOTERIX GENETIC LABORATORIES LLC;YANG, HAI-SU;HORTEN, BRUCE;SCHOLL, THOMAS |
发明人 |
YANG, HAI-SU;HORTEN, BRUCE;SCHOLL, THOMAS |
分类号 |
G01N33/48;G01N33/53 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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