| 摘要 |
PROBLEM TO BE SOLVED: To provide a 5-HT receptor modulator having excellent bioavailability and CNS permeability, and that is selective, highly affinitive and metabolically stable by having in vivo and excellent pharmacokinetic property.SOLUTION: The new arylpiperazinyl sulfonamide compound is represented by formula (I) [wherein Q is an alkylene amine group, or a linking group consisting of a piperidylmethyl group; Ris an alkyl group of C, a cycloalkyl group of Cor the like; Rand Rare independently hydrogen, Ccycloalkyl group or the like; m is 0, 1, 2, 3, 4, 5 or 6; n is 1, 2, 3, 4, 5 or 6; and p is 0, 1, 2, 3 or 4]. |
