| 发明名称 |
MONOMERS AND OLIGONUCLEOTIDES COMPRISING CYCLOADDITION ADDUCT(S) |
| 摘要 |
The invention features compounds of formula (V) or( XII). In one embodiment, the invention relates compounds and processes for conjugating ligand to oligonucleotide. The invention further relates to methods for treating various disorders and diseases such as viral infections, bacterial infections, parasitic infections, cancers, allergies, autoimmune diseases, immunodeficiencies and immunosuppression. |
| 申请公布号 |
WO2011100131(A9) |
申请公布日期 |
2011.10.20 |
| 申请号 |
WO2011US22975 |
申请日期 |
2011.01.28 |
| 申请人 |
ALNYLAM PHARMACUTICALS, INC.;MANOHARAN, MUTHIAH;JAYAPRAKASH, NARAYANANNAIR K.;RAJEEV, KALLANTHOTTAHIL G.;JUNG, MICHAEL E. |
发明人 |
MANOHARAN, MUTHIAH;JAYAPRAKASH, NARAYANANNAIR K.;RAJEEV, KALLANTHOTTAHIL G.;JUNG, MICHAEL E. |
| 分类号 |
A61K47/48;C07D249/04;C07H5/04 |
主分类号 |
A61K47/48 |
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