发明名称 |
WATER SOLUBLE CURCUMIN COMPOSITIONS FOR USE IN ANTI-CANCER AND ANTI-INFLAMMATORY THERAPY |
摘要 |
The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumour and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases. In a fifth aspect, the present invention relates to the use of a pharmaceutical composition comprising said water soluble curcumin derivatives in the treatment of cancer and inflammatory diseases and to a new pharmaceutical composition comprising said water soluble curcumin derivatives.
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申请公布号 |
US2011257126(A1) |
申请公布日期 |
2011.10.20 |
申请号 |
US20090995126 |
申请日期 |
2009.05.26 |
申请人 |
UNIVERSITE DE LIEGE;UNIVERSITE LIBRE DE BRUXELLES |
发明人 |
NEVEN PHILIPPE;SERTEYN DIDIER;DELARGE JACQUES;SCHEER EVA;KISS ROBERT;MATHIEU VERONIQUE;CATALDO DIDIER;ROCKS NATACHA |
分类号 |
A61K31/724;A61P1/00;A61P3/10;A61P9/10;A61P17/06;A61P19/02;A61P25/00;A61P25/16;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/06;A61P37/08;C08B37/16 |
主分类号 |
A61K31/724 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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