发明名称 |
TREATMENT OF CANCERS HAVING K-RAS MUTATIONS |
摘要 |
The present invention provides a method of treating a cancer associated with a K- ras mutation in a subject in need thereof. The method comprises the steps of (1) identifying a subject with a cancer associated with a K-ras mutation; and (2) adminsiterign to the subject (i) an inhibitor of PI3 kinase and (ii) an HDAC inhibitor, wherein the PI3 kinase inhibitor and the HDAC inhibitor are administered in amounts which together are therapeutically effective.
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申请公布号 |
CA2795952(A1) |
申请公布日期 |
2011.10.20 |
申请号 |
CA20112795952 |
申请日期 |
2011.04.15 |
申请人 |
CURIS, INC. |
发明人 |
BAO, RUDI;LAI, CHENGJUNG;QIAN, CHANGGENG |
分类号 |
A61K31/5377;A61K31/519;A61K31/538;A61K31/5383;A61K31/541;A61P35/00 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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