发明名称 |
METHODS AND COMPOSITIONS CONTAINING MTOR INHIBITORS FOR ENHANCING IMMUNE RESPONSES |
摘要 |
<p>Provided are compositions and methods for enhancing immune responses to an antigen. The compositions contain an isolated population of CD8+T cells and an inhibitor of mammalian target of rapamycin (mTOR). The method for obtaining an enhanced immune response to an antigen in an individual entails administering to the individual the antigen and an inhibitor of mammalian target of rapamycin (mTOR). CD8+T cells may also be used for adoptive cell transfer (ACT) therapy.</p> |
申请公布号 |
EP2375897(A1) |
申请公布日期 |
2011.10.19 |
申请号 |
EP20100732083 |
申请日期 |
2010.01.14 |
申请人 |
HEALTH RESEARCH, INC. |
发明人 |
KIM, HYUNG;SHRIKANT, PROTUL;WANG, YANPING;LI, QINGSHENG;RAO, RAJESH |
分类号 |
A61K31/436;A61K35/26;A61K38/20;A61K39/00;A61K39/39;A61P35/00;A61P37/04;C12N5/0783 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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