SUBSTITUTED PIPERIDINES AS CCR3 ANTAGONISTS.

摘要

Object of the present invention are novel substituted compounds of the formula 1, wherein A, R¹, R², R³ and R⁴ are defined as in the description. Another object of the present invention is to provide antagonists of CCR3, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.