发明名称 |
A METHOD OF TREATING INSOMNIA |
摘要 |
<p>A method of treating insomnia comprising administering to a subject a formulation including zaleplon, wherein the formulation is adapted to release the zaleplon after a lag time of at least about one hour after administration of the formulation, and during which substantially no drug substance is released; provide a time of peak plasma concentration of about 3 hours to about 6 hours after administration; provide an elimination half-life after the time of peak plasma concentration of about 0.5 hours to about 0.3 hours; and provide an area under the curve of about 70 ng·h/mL to about 90 ng·h/mL.</p> |
申请公布号 |
EP2375903(A1) |
申请公布日期 |
2011.10.19 |
申请号 |
EP20090835582 |
申请日期 |
2009.12.15 |
申请人 |
SOMNUS THERAPEUTICS, INC. |
发明人 |
CUPIT, GARY;MCCORMICK, ANNE;OSBAKKEN, MARY;BLUMHARDT, CHRISTINE |
分类号 |
A61K31/519;A61K9/28;A61P43/00 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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