发明名称 |
Transdermal delivery system for polynucleotides |
摘要 |
A system for intradermal or transdermal delivery of oligonucleotides or polynucleotides and methods of use thereof employ an apparatus that generates micro-channels in the skin of a subject in conjunction with a pharmaceutical composition comprising an oligonucleotide or polynucleotide, wherein the oligonucleotide or polynucleotide can be delivered into the organism through the micro-channels. The system and methods achieve expression of target proteins encoded by the polynucleotides, and hence are useful in immunization and gene therapy.
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申请公布号 |
US8041421(B2) |
申请公布日期 |
2011.10.18 |
申请号 |
US20050597431 |
申请日期 |
2005.01.25 |
申请人 |
TRANSPHARMA MEDICAL LTD. |
发明人 |
BIRCHALL JAMES;LEVIN GALIT;GERSHONOWITZ AMIKAM |
分类号 |
A61N1/30;A61M31/00;A61N1/32;C07H |
主分类号 |
A61N1/30 |
代理机构 |
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代理人 |
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地址 |
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