The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.
申请公布号
CA2590939(C)
申请公布日期
2011.10.18
申请号
CA20052590939
申请日期
2005.12.16
申请人
AMGEN INC.
发明人
SMITH, ADRIAN LEONARD;BRENNAN, PAUL EDWARD;DEMORIN, FRENEL FILS;LIU, GANG;PARAS, NICK A.;RETZ, DANIEL MARTIN;RAINBEAU, ELIZABETH