发明名称 |
Signal amplification using a synthetic zymogen |
摘要 |
Described herein are zymogens, methods of use for zymogens, and devices that incorporate zymogens. The zymogens include a substrate and an enzyme. The substrate can inhibit the enzyme and is a target for a protein produced by a microorganism. When the substrate is modified by a protein produced by a microorganism, the enzyme is activated. The zymogens can be used to amplify detection assays.
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申请公布号 |
US8039228(B2) |
申请公布日期 |
2011.10.18 |
申请号 |
US20040570075 |
申请日期 |
2004.09.02 |
申请人 |
EXPRESSIVE CONSTRUCTS, INC. |
发明人 |
COLPAS GERARD J.;SEBASTIAN SHITE;SANDERS MITCHELL C. |
分类号 |
C12Q1/66;C12Q1/04;G01N33/542;G01N33/543;G01N33/58;G01N33/68 |
主分类号 |
C12Q1/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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