发明名称 Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
摘要 Methods are provided for drying a particle. Specifically, there is provided a spray-dried diketopiperazine-insulin particle formulation having improved aerodynamic performance and in which the active agent is more stabile and efficiently delivered as compared to that of the lyophilized diketopiperazine-insulin formulation. The dry powders have utility as pharmaceutical formulations for pulmonary delivery.
申请公布号 US8039431(B2) 申请公布日期 2011.10.18
申请号 US20070678046 申请日期 2007.02.22
申请人 MANNKIND CORPORATION 发明人 WILSON BRYAN R.;GRANT MARSHALL
分类号 A61K38/28;G03G13/08 主分类号 A61K38/28
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