COMPOSITIONS AND METHODS RELATED TO PROTEIN A (SPA) ANTIBODIES AS AN ENHANCER OF IMMUNE RESPONSE
摘要
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.
申请公布号
WO2011127032(A1)
申请公布日期
2011.10.13
申请号
WO2011US31213
申请日期
2011.04.05
申请人
UNIVERSITY OF CHICAGO;SCHNEEWIND, OLAF;CHENG, ALICE;MISSIAKAS, DOMINIQUE, M.;KIM, HWAN