发明名称 |
MOLECULAR MODULATORS OF THE WNT/BETA-CATENIN PATHWAY |
摘要 |
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject at least one compound selected from the group consisting of those set forth in Table 1, Table 2, Table 3, and a pharmaceutically acceptable salt thereof. A method of similarly modulating the Wnt/β-catenin pathway in a subject is also discussed.
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申请公布号 |
US2011251144(A1) |
申请公布日期 |
2011.10.13 |
申请号 |
US200913119206 |
申请日期 |
2009.09.16 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;UNIVERSITY OF WASHINGTON |
发明人 |
MOON RANDALL T.;BIECHELE TRAVIS L.;CAMP NATHAN D.;HAGGARTY STEPHEN;FASS DANIEL |
分类号 |
A61K31/7048;A61K31/167;A61K31/197;A61K31/203;A61K31/424;A61K31/428;A61K31/4406;A61K31/444;A61K31/495;A61K31/52;A61K31/553;A61K31/663;A61P1/02;A61P3/10;A61P7/00;A61P17/14;A61P19/08;A61P25/00;A61P25/24;A61P25/28;A61P31/18;A61P35/00;A61P35/02 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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