发明名称 BENZIMIDAZOLE COMPOUND AND ITS USE AS CHROMATOGRAPHIC LIGAND
摘要 PROBLEM TO BE SOLVED: To provide a solid phase matrix used for isolating and/or purifying immunoglobulins with high efficiency and high purity, and to provide a method therefor.SOLUTION: The solid phase matrix is represented by general formula M-SP-L [wherein M is a matrix skeleton; SP is a spacer; L is a ligand represented by the structural formula (I) (Ris -Z-N(R)or the like; Ris -H, -halogen, -OR, -NH, -alkyl, -NO, -SOH, -N(R)C(O)N(R), triazole or the like; R, Rand Rare -H or (un)substituted alkyl; Z is single bond, (un)substituted alkylene, (un)substituted alkenylene or (un)substituted alkynylene; and n is 0 to 4) or a tautomer thereof]. The method for use of the matrix is also provided.
申请公布号 JP2011201885(A) 申请公布日期 2011.10.13
申请号 JP20110093394 申请日期 2011.04.19
申请人 MILLIPORE (UK) LTD 发明人 DUFFIN GORDON R;VICTORIA JANE HENDERSON;ANGUS KATHERINE LOUISE;LYDDIATT ANDREW
分类号 A61K39/395;C07D235/06;C07D235/30;C07D403/04;C07K1/22;C08B37/12 主分类号 A61K39/395
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