发明名称 |
SYNTHESIS OF 18F-LABELED TRACERS IN HYDROUS ORGANIC SOLVENTS |
摘要 |
<p>A method for synthesizing an 18F-labeled probe. The method includes a step of eluting an amount of 18F with a first solvent which includes a predetermined amount of water and at least one organic solvent. In this step, the 18F elutes as an 18F solution. The method also includes a step of using the 18F solution to perform 18F-labeling in the presence of at least one labeling reagent and at least one phase transfer catalyst so as to generate the 18F-labeled probe. In the method, there is no step of drying the 18F starting from a time when the eluting step is performed and ending at a time when the 18F-labeling step is performed.</p> |
申请公布号 |
CA2795762(A1) |
申请公布日期 |
2011.10.13 |
申请号 |
CA20112795762 |
申请日期 |
2011.04.08 |
申请人 |
SIEMENS MEDICAL SOLUTIONS USA, INC. |
发明人 |
GANGADHARMATH, UMESH B.;KOLB, HARTMUTH C.;WALSH, JOSEPH C. |
分类号 |
G01N33/534;A61K51/00;B01D15/36 |
主分类号 |
G01N33/534 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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