| 摘要 |
Provided is a process for the preparation of optically active 2,3-bisphosphinopyrazine derivatives, which is industrially advantageous and by which any isomer can be easily prepared. Specifically provided is a process for the preparation of optically active 2,3-bisphosphinopyrazine derivatives represented by general formula (A), which comprises the following steps (I), (II) and (III). In the formulae, R1 and R2 are a pair of groups that develops asymmetry on the phosphorus atom or that makes the phosphorus atom one point on an asymmetric plane, and are each hydrogen, a hydrocarbon group, or a substituted hydrocarbon group; R3 is an asymmetric hydrocarbon group or a substituted asymmetric hydrocarbon group; R4 and R5 are each hydrogen or alkyl, or alternatively R4 and R5 may be united to form a saturated or unsaturated ring; and X is a halogen atom. |
