| 发明名称 |
PURINE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE |
| 摘要 |
The invention encompasses purine derivatives as gamma secretase modulators, useful for treating diseases associated with the deposition of beta-amyloid peptide in the brain, such as Alzheimer's disease, or of preventing or delaying the onset of dementia associated with such diseases. Pharmaceutical compositions and methods of use are included. |
| 申请公布号 |
US2011251172(A1) |
申请公布日期 |
2011.10.13 |
| 申请号 |
US200913058232 |
申请日期 |
2009.07.31 |
| 申请人 |
|
发明人 |
RIVKIN ALEXEY A.;AHEARN SEAN P.;CHICHETTI STEPHANIE M.;HAMBLETT CHRISTOHPHER L.;GARCIA YUDITH;MARTINEZ MICHELLE;MUNOZ BENITO |
| 分类号 |
A61K31/52;A61K31/5377;A61K31/55;A61K31/551;A61P25/28;C07D473/16 |
主分类号 |
A61K31/52 |
| 代理机构 |
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代理人 |
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| 地址 |
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