ANTITUMORAL COMPOUNDS OF TESTOSTERONE AND CHEMOTHERAPEUTIC DRUGS

摘要

The present invention can be used as an antitumoral medicament for testosterone-dependent tumours, in particular prostate cancer. The invention is a molecular compound formed by testosterone molecules chemically linked to molecules of a chemotherapeutic drug by means of intercalating alkyl molecules with three or more carbons, and aims at combating testosterone-dependent tumours, in particular prostate cancer, eliminating the undesirable effect of tumour resistance to the efflux of known chemotherapeutic compounds. The main contribution of the invention is the use of testosterone as a carrier for the chemotherapeutic drug. In particular, a testosterone molecule chemically linked to a 9-aminoacridine molecule by means of an intercalating alkyl molecule with three or more carbons is used, as an example of one of the compounds that can be produced according to the invention described.